Thirty-five years ago Harold E. Varmus [wikipedia], along with J. Michael Bishop, discovered the role of oncogenes in cancer. That seminal discovery in 1975 gave cancer researchers a path, "the road to be taken," that has today led to great advancements in clinical oncology; it has changed the face of a growing number of cancer types to potentially curable or manageable forms. Not long ago, both scientists were honored with the Nobel Prize in Medicine in 1989 [read, [here, here]