Common Mutations Drive 12 Different Cancer Types

Cancer types from leukemia to breast cancer, and bladder cancer to lung cancer are all driven by a common set of genes containing driver mutations. Researchers from The Cancer Genome Network (TCGN) sequenced and analyzed genomes of 3,281 tumors from 12 different cancer types and discovered 127 genes that were involved in the initiation or progression of these cancers. This research appears in the October 17, 2013, issue of the journal Nature. 

Cancer Meetings and Conferences 2013 (Archived)

Archived list below.

***For upcoming meetings list, go to page 

 http://www.missiontumor.com/p/upcoming-meeting-and-conferences.html

How does ARIAD's Ponatinib (Iclusig) Work

Mechanism of Action Series: Ponatinib

Ariad Pharmaceuticals' leukemia drug ponatinib has been in the news lately for major toxicity fears that can potentially derail its further clinical development. While these issues will be sorted out in coming months, it's a good time to review how does this drug work.

Ponatinib is a pan-inhibitor of native and T315I mutant forms of BCR-ABL kinase.

The Effect of US Congressional Tantrums on Science

Here is one snapshot of what their childish behavior can do. (Let's hope the next generation of congressmen and congresswomen are smarter than this bunch.)